Polycomb protein RING1A limits hematopoietic differentiation in myelodysplastic syndromes

Genetic lesions affecting epigenetic regulators are frequent in myelodysplastic syndromes (MDS). Polycomb proteins are key epigenetic regulators of differentiation and stemness that act as two multimeric complexes termed polycomb repressive complexes 1 and 2, PRC1 and PRC2, respectively. While compo...

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Detalles Bibliográficos
Autores principales: Palau, Anna, Garz, Anne-Kathrin, Diesch, Jeannine, Zwick, Anabel, Malinverni, Roberto, Valero, Vanesa, Lappin, Katrina, Casquero, Raquel, Lennartsson, Andreas, Zuber, Johannes, Navarro, Tomàs, Mills, Ken I., Götze, Katharina S., Buschbeck, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777749/
https://www.ncbi.nlm.nih.gov/pubmed/29383137
http://dx.doi.org/10.18632/oncotarget.22839

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