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Discovering drugs to overcome chemoresistance in ovarian cancers based on the cancer genome atlas tumor transcriptome profile

Ovarian cancer accounts for the highest mortality among gynecologic cancers, mainly due to intrinsic or acquired chemoresistance. While mechanistic-based methods have been used to identify compounds that can overcome chemoresistance, an effective comprehensive drug screening has yet to be developed....

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Detalles Bibliográficos
Autores principales: Wang, Fan, Chang, Jeremy T-H., Zhang, Zhenyu, Morrison, Gladys, Nath, Aritro, Bhutra, Steven, Huang, Rong Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777757/
https://www.ncbi.nlm.nih.gov/pubmed/29383145
http://dx.doi.org/10.18632/oncotarget.22870