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Stabilization of Sur8 via PKCα/δ degradation promotes transformation and migration of colorectal cancer cells

Scaffold proteins of the mitogen activated protein kinase (MAPK) pathway recruit protein kinase cascades to confer context-specificity to cellular signaling. Varying concentrations of scaffold proteins determine different aspects of signaling outputs. However, regulatory mechanisms of scaffold prote...

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Detalles Bibliográficos
Autores principales:	Lee, Kug Hwa, Jeong, Woo-Jeong, Cha, Pu-Hyeon, Lee, Sang-Kyu, Min, Do Sik, Choi, Kang-Yell
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777796/ https://www.ncbi.nlm.nih.gov/pubmed/29383184 http://dx.doi.org/10.18632/oncotarget.23313

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