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Anti-tumor efficacy of oncolytic reovirus against gastrointestinal stromal tumor cells

Imatinib, a multitargeted receptor tyrosine kinase inhibitor, is used as the standard initial therapy against inoperable gastrointestinal stromal tumor (GIST). However, GIST can acquire resistance to imatinib within several years of therapy. The development of oncolytic reovirus as an anticancer age...

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Detalles Bibliográficos
Autores principales:	Inagaki, Yusuke, Kubota, Eiji, Mori, Yoshinori, Aoyama, Mineyoshi, Kataoka, Hiromi, Johnston, Randal N., Joh, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777799/ https://www.ncbi.nlm.nih.gov/pubmed/29383187 http://dx.doi.org/10.18632/oncotarget.23361

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