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Over-expression of PPAR-γ2 gene enhances the adipogenic differentiation of hemangioma-derived mesenchymal stem cells in vitro and in vivo

BACKGROUND: Most of infantile hemangiomas involute into fibrofatty tissue in childhood, which indicates adipogenesis during this period. Mesenchymal stem cells (MSCs) contribute to the adipogenesis in IH. In this study, we investigated the effects of overexpression of PPAR-γ2 gene on the adipogenic...

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Detalles Bibliográficos
Autores principales: Yuan, Si-Ming, Guo, Yao, Wang, Qian, Xu, Yuan, Wang, Min, Chen, Hai-Ni, Shen, Wei-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777815/
https://www.ncbi.nlm.nih.gov/pubmed/29383203
http://dx.doi.org/10.18632/oncotarget.23705