Keratinocytes mediate innocuous and noxious touch via ATP-P2X4 signaling

The first point of our body’s contact with tactile stimuli (innocuous and noxious) is the epidermis, the outermost layer of skin that is largely composed of keratinocytes. Here, we sought to define the role that keratinocytes play in touch sensation in vivo and ex vivo. We show that optogenetic inhi...

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Detalles Bibliográficos
Autores principales: Moehring, Francie, Cowie, Ashley M, Menzel, Anthony D, Weyer, Andy D, Grzybowski, Michael, Arzua, Thiago, Geurts, Aron M, Palygin, Oleg, Stucky, Cheryl L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777822/
https://www.ncbi.nlm.nih.gov/pubmed/29336303
http://dx.doi.org/10.7554/eLife.31684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777822/
https://www.ncbi.nlm.nih.gov/pubmed/29336303
http://dx.doi.org/10.7554/eLife.31684

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