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Delayed onset of autoreactive antibody production and M2-skewed macrophages contribute to improved survival of TACI deficient MRL-Fas/Lpr mouse

Anti-B cell activating factor belonging to TNF-family (BAFF) antibody therapy is indicated for the treatment of patients with active systemic lupus erythematosus (SLE). We hypothesized that the BAFF receptor, transmembrane activator and calcium-modulator and cyclophilin interactor (TACI) may be resp...

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Detalles Bibliográficos
Autores principales:	Liu, Lunhua, Allman, Windy Rose, Coleman, Adam Steven, Takeda, Kazuyo, Lin, Tsai-Lien, Akkoyunlu, Mustafa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778001/ https://www.ncbi.nlm.nih.gov/pubmed/29358664 http://dx.doi.org/10.1038/s41598-018-19827-8

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