Lysophosphatidylcholine acyltransferase 2-mediated lipid droplet production supports colorectal cancer chemoresistance

Lipid droplet (LD) accumulation is a now well-recognised hallmark of cancer. However, the significance of LD accumulation in colorectal cancer (CRC) biology is incompletely understood under chemotherapeutic conditions. Since drug resistance is a major obstacle to treatment success, we sought to dete...

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Detalles Bibliográficos
Autores principales: Cotte, Alexia Karen, Aires, Virginie, Fredon, Maxime, Limagne, Emeric, Derangère, Valentin, Thibaudin, Marion, Humblin, Etienne, Scagliarini, Alessandra, de Barros, Jean-Paul Pais, Hillon, Patrick, Ghiringhelli, François, Delmas, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778070/
https://www.ncbi.nlm.nih.gov/pubmed/29358673
http://dx.doi.org/10.1038/s41467-017-02732-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778070/
https://www.ncbi.nlm.nih.gov/pubmed/29358673
http://dx.doi.org/10.1038/s41467-017-02732-5

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