Development of matrix metalloproteinase-targeted probes for lung inflammation detection with positron emission tomography

As matrix metalloproteinases (MMPs), especially MMP-9 and MMP-12 are involved in the pathological processes associated with chronic obstructive pulmonary disease (COPD), we developed a novel radiofluorinated probe, (18)F-IPFP, for MMPs-targeted positron emission tomography (PET). (18)F-IPFP was desi...

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Detalles Bibliográficos
Autores principales: Kondo, Naoya, Temma, Takashi, Aita, Kazuki, Shimochi, Saeka, Koshino, Kazuhiro, Senda, Michio, Iida, Hidehiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778071/
https://www.ncbi.nlm.nih.gov/pubmed/29358724
http://dx.doi.org/10.1038/s41598-018-19890-1

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