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Positioning of proteasome inhibitors in therapy of solid malignancies
Targeting of the protein degradation pathway, in particular, the ubiquitin-proteasome system, has emerged as an attractive novel cancer chemotherapeutic modality. Although proteasome inhibitors have been most successfully applied in the treatment of hematological malignancies, they also received con...
Autores principales: | Roeten, Margot S. F., Cloos, Jacqueline, Jansen, Gerrit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778165/ https://www.ncbi.nlm.nih.gov/pubmed/29184971 http://dx.doi.org/10.1007/s00280-017-3489-0 |
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