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Model based analysis of the heterogeneity in the tumour size dynamics differentiates vemurafenib, dabrafenib and trametinib in metastatic melanoma

PURPOSE: Explore the heterogeneity in dynamics of tumour response to vemurafenib, dabrafenib and trametinib using routinely collected clinical trial imaging data. METHODS: Time-series imaging data from the phase III studies of vemurafenib, dabrafenib and trametinib were collected through a data repo...

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Detalles Bibliográficos
Autores principales:	Mistry, Hitesh B., Orrell, David, Eftimie, Raluca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778167/ https://www.ncbi.nlm.nih.gov/pubmed/29222604 http://dx.doi.org/10.1007/s00280-017-3486-3

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