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Misfolding and aggregation of nascent proteins: a novel mode of toxic cadmium action in vivo

Cadmium is a highly poisonous metal and a human carcinogen, but the molecular mechanisms underlying its cellular toxicity are not fully understood. Recent findings in yeast cells indicate that cadmium exerts its deleterious effects by inducing widespread misfolding and aggregation of nascent protein...

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Detalles Bibliográficos
Autores principales: Tamás, Markus J., Fauvet, Bruno, Christen, Philipp, Goloubinoff, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778182/
https://www.ncbi.nlm.nih.gov/pubmed/28936749
http://dx.doi.org/10.1007/s00294-017-0748-x