Cargando…
Misfolding and aggregation of nascent proteins: a novel mode of toxic cadmium action in vivo
Cadmium is a highly poisonous metal and a human carcinogen, but the molecular mechanisms underlying its cellular toxicity are not fully understood. Recent findings in yeast cells indicate that cadmium exerts its deleterious effects by inducing widespread misfolding and aggregation of nascent protein...
Autores principales: | Tamás, Markus J., Fauvet, Bruno, Christen, Philipp, Goloubinoff, Pierre |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778182/ https://www.ncbi.nlm.nih.gov/pubmed/28936749 http://dx.doi.org/10.1007/s00294-017-0748-x |
Ejemplares similares
-
Heavy Metals and Metalloids As a Cause for Protein Misfolding and Aggregation
por: Tamás, Markus J., et al.
Publicado: (2014) -
Recent and future grand challenges in protein folding, misfolding, and degradation
por: Goloubinoff, Pierre
Publicado: (2014) -
Bacterial Hsp90 Facilitates the Degradation of Aggregation-Prone Hsp70–Hsp40 Substrates
por: Fauvet, Bruno, et al.
Publicado: (2021) -
Molecular chaperones are nanomachines that catalytically unfold misfolded and alternatively folded proteins
por: Mattoo, Rayees U. H., et al.
Publicado: (2014) -
Quantitative proteomic analysis to capture the role of heat‐accumulated proteins in moss plant acquired thermotolerance
por: Guihur, Anthony, et al.
Publicado: (2020)