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Protective Effect of Klotho against Ischemic Brain Injury Is Associated with Inhibition of RIG-I/NF-κB Signaling

Aging is the greatest independent risk factor for the occurrence of stroke and poor outcomes, at least partially through progressive increases in oxidative stress and inflammation with advanced age. Klotho is an antiaging gene, the expression of which declines with age. Klotho may protect against ne...

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Detalles Bibliográficos
Autores principales:	Zhou, Hong-Jing, Li, Hui, Shi, Meng-Qi, Mao, Xiao-Na, Liu, Dong-Ling, Chang, Yi-Ran, Gan, Yu-Miao, Kuang, Xi, Du, Jun-Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778393/ https://www.ncbi.nlm.nih.gov/pubmed/29403373 http://dx.doi.org/10.3389/fphar.2017.00950

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