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Universal correction of enzymatic sequence bias reveals molecular signatures of protein/DNA interactions
Coupling molecular biology to high-throughput sequencing has revolutionized the study of biology. Molecular genomics techniques are continually refined to provide higher resolution mapping of nucleic acid interactions and structure. Sequence preferences of enzymes can interfere with the accurate int...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778497/ https://www.ncbi.nlm.nih.gov/pubmed/29126307 http://dx.doi.org/10.1093/nar/gkx1053 |