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Biochemical and structural characterization of a novel cooperative binding mode by Pit-1 with CATT repeats in the macrophage migration inhibitory factor promoter

Overexpression of the proinflammatory cytokine macrophage migration inhibitory factor (MIF) is linked to a number of autoimmune diseases and cancer. MIF production has been correlated to the number of CATT repeats in a microsatellite region upstream of the MIF gene. We have characterized the interac...

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Detalles Bibliográficos
Autores principales:	Agarwal, Sorabh, Cho, Thomas Yoonsang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778499/ https://www.ncbi.nlm.nih.gov/pubmed/29186613 http://dx.doi.org/10.1093/nar/gkx1183

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