Cargando…
LncRNA lnc-RI regulates homologous recombination repair of DNA double-strand breaks by stabilizing RAD51 mRNA as a competitive endogenous RNA
DNA double-strand break (DSB) repair is critical for the maintenance of genome stability. The current models of the mechanism of DSB repair are based on studies of DNA repair proteins. Long non-coding RNAs (lncRNAs) have recently emerged as new regulatory molecules, with diverse functions in biologi...
Autores principales: | Shen, Liping, Wang, Qi, Liu, Ruixue, Chen, Zhongmin, Zhang, Xueqing, Zhou, Pingkun, Wang, Zhidong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778505/ https://www.ncbi.nlm.nih.gov/pubmed/29216366 http://dx.doi.org/10.1093/nar/gkx1224 |
Ejemplares similares
-
GEMIN2 promotes accumulation of RAD51 at double-strand breaks in homologous recombination
por: Takizawa, Yoshimasa, et al.
Publicado: (2010) -
RI-1: a chemical inhibitor of RAD51 that disrupts homologous recombination in human cells
por: Budke, Brian, et al.
Publicado: (2012) -
Homologous recombination in budding yeast expressing the human RAD52 gene reveals a Rad51-independent mechanism of conservative double-strand break repair
por: Manthey, Glenn M., et al.
Publicado: (2017) -
DIDS, a chemical compound that inhibits RAD51-mediated homologous pairing and strand exchange
por: Ishida, Takako, et al.
Publicado: (2009) -
LncRNA HOTAIRM1 functions in DNA double-strand break repair via its association with DNA repair and mRNA surveillance factors
por: Chuang, Tzu-Wei, et al.
Publicado: (2023)