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Computational Pipeline for the PGV-001 Neoantigen Vaccine Trial

This paper describes the sequencing protocol and computational pipeline for the PGV-001 personalized vaccine trial. PGV-001 is a therapeutic peptide vaccine targeting neoantigens identified from patient tumor samples. Peptides are selected by a computational pipeline that identifies mutations from t...

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Detalles Bibliográficos
Autores principales:	Rubinsteyn, Alex, Kodysh, Julia, Hodes, Isaac, Mondet, Sebastien, Aksoy, Bulent Arman, Finnigan, John P., Bhardwaj, Nina, Hammerbacher, Jeffrey
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778604/ https://www.ncbi.nlm.nih.gov/pubmed/29403468 http://dx.doi.org/10.3389/fimmu.2017.01807

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