Protein complex scaffolding predicted as a prevalent function of long non-coding RNAs

The human transcriptome contains thousands of long non-coding RNAs (lncRNAs). Characterizing their function is a current challenge. An emerging concept is that lncRNAs serve as protein scaffolds, forming ribonucleoproteins and bringing proteins in proximity. However, only few scaffolding lncRNAs hav...

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Detalles Bibliográficos
Autores principales: Ribeiro, Diogo M, Zanzoni, Andreas, Cipriano, Andrea, Delli Ponti, Riccardo, Spinelli, Lionel, Ballarino, Monica, Bozzoni, Irene, Tartaglia, Gian Gaetano, Brun, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778612/
https://www.ncbi.nlm.nih.gov/pubmed/29165713
http://dx.doi.org/10.1093/nar/gkx1169

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