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A remarkable response to pazopanib, despite recurrent liver toxicity, in a patient with a high grade endometrial stromal sarcoma, a case report
BACKGROUND: Pazopanib is an oral tyrosine kinase inhibitor registered for metastatic renal cell carcinoma and soft tissue sarcoma. Liver toxicity is a common side effect for this class of agents. The current opinion is that in case of severe liver toxicity pazopanib should be interrupted and restart...
Autores principales: | Verschoor, Arie J., Warmerdam, Fabiënne A. R. M., Bosse, Tjalling, Bovée, Judith V. M. G., Gelderblom, Hans |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778698/ https://www.ncbi.nlm.nih.gov/pubmed/29357824 http://dx.doi.org/10.1186/s12885-018-3999-0 |
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