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Cell adhesion-mediated mitochondria transfer contributes to mesenchymal stem cell-induced chemoresistance on T cell acute lymphoblastic leukemia cells

BACKGROUND: Despite the high cure rate of T cell acute lymphoblastic leukemia (T-ALL), drug resistance to chemotherapy remains a significant clinical problem. Bone marrow mesenchymal stem cells (MSCs) protect leukemic cells from chemotherapy, but the underlying mechanisms are poorly understood. In t...

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Detalles Bibliográficos
Autores principales: Wang, Jiancheng, Liu, Xin, Qiu, Yuan, Shi, Yue, Cai, Jianye, Wang, Boyan, Wei, Xiaoyue, Ke, Qiong, Sui, Xin, Wang, Yi, Huang, Yinong, Li, Hongyu, Wang, Tao, Lin, Ren, Liu, Qifa, Xiang, Andy Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778754/
https://www.ncbi.nlm.nih.gov/pubmed/29357914
http://dx.doi.org/10.1186/s13045-018-0554-z