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Metformin inhibits the migration and invasion of esophageal squamous cell carcinoma cells by downregulating the protein kinase B signaling pathway

Previous studies have suggested that metformin, a biguanide family member widely used as an oral antidiabetic drug, may inhibit proliferation and induce apoptosis in certain types of cancer cell. However, the molecular mechanisms underlying metformin-associated anticancer effects, and in particular...

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Detalles Bibliográficos
Autores principales: He, Yindi, Tan, Xiaojun, Hu, Hui, Wang, Qinjia, Hu, Xi, Cai, Xianbin, Guan, Yinghong, Chen, Binming, Jing, Xubin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778829/
https://www.ncbi.nlm.nih.gov/pubmed/29435022
http://dx.doi.org/10.3892/ol.2017.7699

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