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Induction of apoptosis by an oleanolic acid derivative in SMMC-7721 human hepatocellular carcinoma cells is associated with mitochondrial dysfunction
The aim of the present study was to investigate the effects of an oleanolic acid derivative, a novel antitumor drug, on the growth of SMMC-7721 human hepatocellular carcinoma cells and the underlying mechanism. An MTT assay was performed to determine the cytotoxicity of the oleanolic acid derivative...
Autores principales: | Fan, Xinfeng, Wang, Penglong, Sun, Yaogui, Jiang, Junbing, Du, Haiyuan, Wang, Zhirui, Duan, Zhibian, Lei, Haimin, Li, Hongquan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778847/ https://www.ncbi.nlm.nih.gov/pubmed/29467861 http://dx.doi.org/10.3892/ol.2017.7653 |
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