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Vulnerability to the transmission of human visceral leishmaniasis in a Brazilian urban area
OBJECTIVE: To analyze the determinants for the occurrence of human visceral leishmaniasis linked to the conditions of vulnerability. METHODS: This is an ecological study, whose spatial analysis unit was the Territorial Analysis Unit in Araguaína, State of Tocantins, Brazil, from 2007 to 2012. We hav...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Faculdade de Saúde Pública da Universidade de São Paulo
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778952/ https://www.ncbi.nlm.nih.gov/pubmed/28513764 http://dx.doi.org/10.1590/S1518-8787.2017051006532 |
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author | de Toledo, Celina Roma Sánchez de Almeida, Andréa Sobral Chaves, Sergio Augusto de Miranda Sabroza, Paulo Chagastelles Toledo, Luciano Medeiros Caldas, Jefferson Pereira |
author_facet | de Toledo, Celina Roma Sánchez de Almeida, Andréa Sobral Chaves, Sergio Augusto de Miranda Sabroza, Paulo Chagastelles Toledo, Luciano Medeiros Caldas, Jefferson Pereira |
author_sort | de Toledo, Celina Roma Sánchez |
collection | PubMed |
description | OBJECTIVE: To analyze the determinants for the occurrence of human visceral leishmaniasis linked to the conditions of vulnerability. METHODS: This is an ecological study, whose spatial analysis unit was the Territorial Analysis Unit in Araguaína, State of Tocantins, Brazil, from 2007 to 2012. We have carried out an analysis of the sociodemographic and urban infrastructure situation of the municipality. Normalized primary indicators were calculated and used to construct the indicators of vulnerability of the social structure, household structure, and urban infrastructure. From them, we have composed a vulnerability index. Kernel density estimation was used to evaluate the density of cases of human visceral leishmaniasis, based on the coordinates of the cases. Bivariate global Moran’s I was used to verify the existence of spatial autocorrelation between the incidence of human visceral leishmaniasis and the indicators and index of vulnerability. Bivariate local Moran’s I was used to identify spatial clusters. RESULTS: We have observed a pattern of centrifugal spread of human visceral leishmaniasis in the municipality, where outbreaks of the disease have progressively reached central and peri-urban areas. There has been no correlation between higher incidences of human visceral leishmaniasis and worse living conditions. Statistically significant clusters have been observed between the incidences of human visceral leishmaniasis in both periods analyzed (2007 to 2009 and 2010 to 2012) and the indicators and index of vulnerability. CONCLUSIONS: The environment in circumscribed areas helps as protection factor or increases the local vulnerability to the occurrence of human visceral leishmaniasis. The use of methodology that analyzes the conditions of life of the population and the spatial distribution of human visceral leishmaniasis is essential to identify the most vulnerable areas to the spread/maintenance of the disease. |
format | Online Article Text |
id | pubmed-5778952 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Faculdade de Saúde Pública da Universidade de São Paulo |
record_format | MEDLINE/PubMed |
spelling | pubmed-57789522018-02-08 Vulnerability to the transmission of human visceral leishmaniasis in a Brazilian urban area de Toledo, Celina Roma Sánchez de Almeida, Andréa Sobral Chaves, Sergio Augusto de Miranda Sabroza, Paulo Chagastelles Toledo, Luciano Medeiros Caldas, Jefferson Pereira Rev Saude Publica Original Articles OBJECTIVE: To analyze the determinants for the occurrence of human visceral leishmaniasis linked to the conditions of vulnerability. METHODS: This is an ecological study, whose spatial analysis unit was the Territorial Analysis Unit in Araguaína, State of Tocantins, Brazil, from 2007 to 2012. We have carried out an analysis of the sociodemographic and urban infrastructure situation of the municipality. Normalized primary indicators were calculated and used to construct the indicators of vulnerability of the social structure, household structure, and urban infrastructure. From them, we have composed a vulnerability index. Kernel density estimation was used to evaluate the density of cases of human visceral leishmaniasis, based on the coordinates of the cases. Bivariate global Moran’s I was used to verify the existence of spatial autocorrelation between the incidence of human visceral leishmaniasis and the indicators and index of vulnerability. Bivariate local Moran’s I was used to identify spatial clusters. RESULTS: We have observed a pattern of centrifugal spread of human visceral leishmaniasis in the municipality, where outbreaks of the disease have progressively reached central and peri-urban areas. There has been no correlation between higher incidences of human visceral leishmaniasis and worse living conditions. Statistically significant clusters have been observed between the incidences of human visceral leishmaniasis in both periods analyzed (2007 to 2009 and 2010 to 2012) and the indicators and index of vulnerability. CONCLUSIONS: The environment in circumscribed areas helps as protection factor or increases the local vulnerability to the occurrence of human visceral leishmaniasis. The use of methodology that analyzes the conditions of life of the population and the spatial distribution of human visceral leishmaniasis is essential to identify the most vulnerable areas to the spread/maintenance of the disease. Faculdade de Saúde Pública da Universidade de São Paulo 2017-05-08 /pmc/articles/PMC5778952/ /pubmed/28513764 http://dx.doi.org/10.1590/S1518-8787.2017051006532 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Articles de Toledo, Celina Roma Sánchez de Almeida, Andréa Sobral Chaves, Sergio Augusto de Miranda Sabroza, Paulo Chagastelles Toledo, Luciano Medeiros Caldas, Jefferson Pereira Vulnerability to the transmission of human visceral leishmaniasis in a Brazilian urban area |
title | Vulnerability to the transmission of human visceral leishmaniasis in a Brazilian urban area |
title_full | Vulnerability to the transmission of human visceral leishmaniasis in a Brazilian urban area |
title_fullStr | Vulnerability to the transmission of human visceral leishmaniasis in a Brazilian urban area |
title_full_unstemmed | Vulnerability to the transmission of human visceral leishmaniasis in a Brazilian urban area |
title_short | Vulnerability to the transmission of human visceral leishmaniasis in a Brazilian urban area |
title_sort | vulnerability to the transmission of human visceral leishmaniasis in a brazilian urban area |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778952/ https://www.ncbi.nlm.nih.gov/pubmed/28513764 http://dx.doi.org/10.1590/S1518-8787.2017051006532 |
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