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Vulnerability to the transmission of human visceral leishmaniasis in a Brazilian urban area

OBJECTIVE: To analyze the determinants for the occurrence of human visceral leishmaniasis linked to the conditions of vulnerability. METHODS: This is an ecological study, whose spatial analysis unit was the Territorial Analysis Unit in Araguaína, State of Tocantins, Brazil, from 2007 to 2012. We hav...

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Autores principales: de Toledo, Celina Roma Sánchez, de Almeida, Andréa Sobral, Chaves, Sergio Augusto de Miranda, Sabroza, Paulo Chagastelles, Toledo, Luciano Medeiros, Caldas, Jefferson Pereira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculdade de Saúde Pública da Universidade de São Paulo 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778952/
https://www.ncbi.nlm.nih.gov/pubmed/28513764
http://dx.doi.org/10.1590/S1518-8787.2017051006532
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author de Toledo, Celina Roma Sánchez
de Almeida, Andréa Sobral
Chaves, Sergio Augusto de Miranda
Sabroza, Paulo Chagastelles
Toledo, Luciano Medeiros
Caldas, Jefferson Pereira
author_facet de Toledo, Celina Roma Sánchez
de Almeida, Andréa Sobral
Chaves, Sergio Augusto de Miranda
Sabroza, Paulo Chagastelles
Toledo, Luciano Medeiros
Caldas, Jefferson Pereira
author_sort de Toledo, Celina Roma Sánchez
collection PubMed
description OBJECTIVE: To analyze the determinants for the occurrence of human visceral leishmaniasis linked to the conditions of vulnerability. METHODS: This is an ecological study, whose spatial analysis unit was the Territorial Analysis Unit in Araguaína, State of Tocantins, Brazil, from 2007 to 2012. We have carried out an analysis of the sociodemographic and urban infrastructure situation of the municipality. Normalized primary indicators were calculated and used to construct the indicators of vulnerability of the social structure, household structure, and urban infrastructure. From them, we have composed a vulnerability index. Kernel density estimation was used to evaluate the density of cases of human visceral leishmaniasis, based on the coordinates of the cases. Bivariate global Moran’s I was used to verify the existence of spatial autocorrelation between the incidence of human visceral leishmaniasis and the indicators and index of vulnerability. Bivariate local Moran’s I was used to identify spatial clusters. RESULTS: We have observed a pattern of centrifugal spread of human visceral leishmaniasis in the municipality, where outbreaks of the disease have progressively reached central and peri-urban areas. There has been no correlation between higher incidences of human visceral leishmaniasis and worse living conditions. Statistically significant clusters have been observed between the incidences of human visceral leishmaniasis in both periods analyzed (2007 to 2009 and 2010 to 2012) and the indicators and index of vulnerability. CONCLUSIONS: The environment in circumscribed areas helps as protection factor or increases the local vulnerability to the occurrence of human visceral leishmaniasis. The use of methodology that analyzes the conditions of life of the population and the spatial distribution of human visceral leishmaniasis is essential to identify the most vulnerable areas to the spread/maintenance of the disease.
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spelling pubmed-57789522018-02-08 Vulnerability to the transmission of human visceral leishmaniasis in a Brazilian urban area de Toledo, Celina Roma Sánchez de Almeida, Andréa Sobral Chaves, Sergio Augusto de Miranda Sabroza, Paulo Chagastelles Toledo, Luciano Medeiros Caldas, Jefferson Pereira Rev Saude Publica Original Articles OBJECTIVE: To analyze the determinants for the occurrence of human visceral leishmaniasis linked to the conditions of vulnerability. METHODS: This is an ecological study, whose spatial analysis unit was the Territorial Analysis Unit in Araguaína, State of Tocantins, Brazil, from 2007 to 2012. We have carried out an analysis of the sociodemographic and urban infrastructure situation of the municipality. Normalized primary indicators were calculated and used to construct the indicators of vulnerability of the social structure, household structure, and urban infrastructure. From them, we have composed a vulnerability index. Kernel density estimation was used to evaluate the density of cases of human visceral leishmaniasis, based on the coordinates of the cases. Bivariate global Moran’s I was used to verify the existence of spatial autocorrelation between the incidence of human visceral leishmaniasis and the indicators and index of vulnerability. Bivariate local Moran’s I was used to identify spatial clusters. RESULTS: We have observed a pattern of centrifugal spread of human visceral leishmaniasis in the municipality, where outbreaks of the disease have progressively reached central and peri-urban areas. There has been no correlation between higher incidences of human visceral leishmaniasis and worse living conditions. Statistically significant clusters have been observed between the incidences of human visceral leishmaniasis in both periods analyzed (2007 to 2009 and 2010 to 2012) and the indicators and index of vulnerability. CONCLUSIONS: The environment in circumscribed areas helps as protection factor or increases the local vulnerability to the occurrence of human visceral leishmaniasis. The use of methodology that analyzes the conditions of life of the population and the spatial distribution of human visceral leishmaniasis is essential to identify the most vulnerable areas to the spread/maintenance of the disease. Faculdade de Saúde Pública da Universidade de São Paulo 2017-05-08 /pmc/articles/PMC5778952/ /pubmed/28513764 http://dx.doi.org/10.1590/S1518-8787.2017051006532 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
de Toledo, Celina Roma Sánchez
de Almeida, Andréa Sobral
Chaves, Sergio Augusto de Miranda
Sabroza, Paulo Chagastelles
Toledo, Luciano Medeiros
Caldas, Jefferson Pereira
Vulnerability to the transmission of human visceral leishmaniasis in a Brazilian urban area
title Vulnerability to the transmission of human visceral leishmaniasis in a Brazilian urban area
title_full Vulnerability to the transmission of human visceral leishmaniasis in a Brazilian urban area
title_fullStr Vulnerability to the transmission of human visceral leishmaniasis in a Brazilian urban area
title_full_unstemmed Vulnerability to the transmission of human visceral leishmaniasis in a Brazilian urban area
title_short Vulnerability to the transmission of human visceral leishmaniasis in a Brazilian urban area
title_sort vulnerability to the transmission of human visceral leishmaniasis in a brazilian urban area
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778952/
https://www.ncbi.nlm.nih.gov/pubmed/28513764
http://dx.doi.org/10.1590/S1518-8787.2017051006532
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