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Long Noncoding RNA Kcna2 Antisense RNA Contributes to Ventricular Arrhythmias via Silencing Kcna2 in Rats With Congestive Heart Failure

BACKGROUND: Congestive heart failure (CHF) is a common cardiovascular disease that is often accompanied by ventricular arrhythmias. The decrease of the slow component of the delayed rectifier potassium current (I(K) (s)) in CHF leads to action potential (AP) prolongation, and the I(K) (s) is an impo...

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Detalles Bibliográficos
Autores principales: Long, Qing‐Qing, Wang, Hao, Gao, Wei, Fan, Yi, Li, Ya‐Fei, Ma, Yao, Yang, Yang, Shi, Hao‐Jie, Chen, Bing‐Rui, Meng, Hao‐Yu, Wang, Qi‐Ming, Wang, Fang, Wang, Ze‐Mu, Wang, Lian‐Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778995/
https://www.ncbi.nlm.nih.gov/pubmed/29263036
http://dx.doi.org/10.1161/JAHA.117.005965