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Topoisomerase IIβ Selectively Regulates Motor Neuron Identity and Peripheral Connectivity through Hox/Pbx-Dependent Transcriptional Programs
Vital motor functions, such as respiration and locomotion, rely on the ability of spinal motor neurons (MNs) to acquire stereotypical positions in the ventral spinal cord and to project with high precision to their peripheral targets. These key properties of MNs emerge during development through tra...
Autores principales: | Edmond, Michaela, Hanley, Olivia, Philippidou, Polyxeni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779120/ https://www.ncbi.nlm.nih.gov/pubmed/29379870 http://dx.doi.org/10.1523/ENEURO.0404-17.2017 |
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