Transient hypothyroidism favors oligodendrocyte generation providing functional remyelination in the adult mouse brain

In the adult brain, both neurons and oligodendrocytes can be generated from neural stem cells located within the Sub-Ventricular Zone (SVZ). Physiological signals regulating neuronal versus glial fate are largely unknown. Here we report that a thyroid hormone (T(3))-free window, with or without a de...

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Detalles Bibliográficos
Autores principales: Remaud, Sylvie, Ortiz, Fernando C, Perret-Jeanneret, Marine, Aigrot, Marie-Stéphane, Gothié, Jean-David, Fekete, Csaba, Kvárta-Papp, Zsuzsanna, Gereben, Balázs, Langui, Dominique, Lubetzki, Catherine, Angulo, Maria Cecilia, Zalc, Bernard, Demeneix, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779229/
https://www.ncbi.nlm.nih.gov/pubmed/28875931
http://dx.doi.org/10.7554/eLife.29996

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