The effect of oral clindamycin and rifampicin combination therapy in patients with hidradenitis suppurativa in Singapore

Hidradenitis suppurativa (HS) is a chronic inflammatory disease of follicular occlusion characterized by abscesses, draining sinuses, and scarring. The efficacy and tolerability of combination treatment with oral clindamycin and rifampicin have previously been assessed in 4 studies including groups...

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Autores principales: Ochi, Harumi, Tan, Lixian Chris, Oon, Hazel H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779281/
https://www.ncbi.nlm.nih.gov/pubmed/29403298
http://dx.doi.org/10.2147/CCID.S136730
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author Ochi, Harumi
Tan, Lixian Chris
Oon, Hazel H
author_facet Ochi, Harumi
Tan, Lixian Chris
Oon, Hazel H
author_sort Ochi, Harumi
collection PubMed
description Hidradenitis suppurativa (HS) is a chronic inflammatory disease of follicular occlusion characterized by abscesses, draining sinuses, and scarring. The efficacy and tolerability of combination treatment with oral clindamycin and rifampicin have previously been assessed in 4 studies including groups of Caucasian patients. Overall results are promising with reported improvement rates between 71.4% and 85.7%. In this study, we propose that combination therapy is safe and efficacious in the treatment of HS, not only among Caucasians, but also in a group of Asian patients in Singapore.
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spelling pubmed-57792812018-02-05 The effect of oral clindamycin and rifampicin combination therapy in patients with hidradenitis suppurativa in Singapore Ochi, Harumi Tan, Lixian Chris Oon, Hazel H Clin Cosmet Investig Dermatol Research Letter Hidradenitis suppurativa (HS) is a chronic inflammatory disease of follicular occlusion characterized by abscesses, draining sinuses, and scarring. The efficacy and tolerability of combination treatment with oral clindamycin and rifampicin have previously been assessed in 4 studies including groups of Caucasian patients. Overall results are promising with reported improvement rates between 71.4% and 85.7%. In this study, we propose that combination therapy is safe and efficacious in the treatment of HS, not only among Caucasians, but also in a group of Asian patients in Singapore. Dove Medical Press 2018-01-18 /pmc/articles/PMC5779281/ /pubmed/29403298 http://dx.doi.org/10.2147/CCID.S136730 Text en © 2018 Ochi et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Research Letter
Ochi, Harumi
Tan, Lixian Chris
Oon, Hazel H
The effect of oral clindamycin and rifampicin combination therapy in patients with hidradenitis suppurativa in Singapore
title The effect of oral clindamycin and rifampicin combination therapy in patients with hidradenitis suppurativa in Singapore
title_full The effect of oral clindamycin and rifampicin combination therapy in patients with hidradenitis suppurativa in Singapore
title_fullStr The effect of oral clindamycin and rifampicin combination therapy in patients with hidradenitis suppurativa in Singapore
title_full_unstemmed The effect of oral clindamycin and rifampicin combination therapy in patients with hidradenitis suppurativa in Singapore
title_short The effect of oral clindamycin and rifampicin combination therapy in patients with hidradenitis suppurativa in Singapore
title_sort effect of oral clindamycin and rifampicin combination therapy in patients with hidradenitis suppurativa in singapore
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779281/
https://www.ncbi.nlm.nih.gov/pubmed/29403298
http://dx.doi.org/10.2147/CCID.S136730
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