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Melanocortin 1 Receptor Deficiency Promotes Atherosclerosis in Apolipoprotein E(−/−) Mice

OBJECTIVE—: The MC1-R (melanocortin 1 receptor) is expressed by monocytes and macrophages where it mediates anti-inflammatory actions. MC1-R also protects against macrophage foam cell formation primarily by promoting cholesterol efflux through the ABCA1 (ATP-binding cassette transporter subfamily A...

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Detalles Bibliográficos
Autores principales:	Rinne, Petteri, Kadiri, James J., Velasco-Delgado, Mauricio, Nuutinen, Salla, Viitala, Miro, Hollmén, Maija, Rami, Martina, Savontaus, Eriika, Steffens, Sabine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2018
Materias:	Basic Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779319/ https://www.ncbi.nlm.nih.gov/pubmed/29284608 http://dx.doi.org/10.1161/ATVBAHA.117.310418

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