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Neuroprotective effect of chondroitin sulfate on SH-SY5Y cells overexpressing wild-type or A53T mutant α-synuclein
Accumulation of α-synuclein (α-SYN) is a common pathology for Parkinson's disease (PD). There is abundant evidence that the toxic-gain-of-function of α-SYN's is associated with aggregation and consequent effects. To assess the potential of chondroitin sulfate (CS) in this regard, the prese...
Autores principales: | Ju, Chuanxia, Gao, Jianjun, Hou, Lin, Wang, Lei, Zhang, Fang, Sun, Fusheng, Zhang, Tingting, Xu, Pingping, Shi, Zhenyan, Hu, Fang, Zhang, Congxiao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779948/ https://www.ncbi.nlm.nih.gov/pubmed/28990084 http://dx.doi.org/10.3892/mmr.2017.7725 |
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