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MACC1 facilitates chemoresistance and cancer stem cell-like properties of colon cancer cells through the PI3K/AKT signaling pathway

With regards to colon cancer, resistance to 5-fluorouracil (5-FU)-based chemotherapy and cancer stem cells (CSCs) are considered important factors underlying therapy failure. Metastasis-associated colon cancer 1 (MACC1) has been associated with poor prognosis and the promotion of metastasis within s...

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Detalles Bibliográficos
Autores principales:	Wang, Jiankai, Wang, Wenjuan, Cai, Hongyi, Du, Binbin, Zhang, Lijuan, Ma, Wen, Hu, Yongguo, Feng, Shifang, Miao, Guoying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779950/ https://www.ncbi.nlm.nih.gov/pubmed/28990068 http://dx.doi.org/10.3892/mmr.2017.7721

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