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Inhibition of neuroblastoma proliferation by PF-3758309, a small-molecule inhibitor that targets p21-activated kinase 4

Neuroblastoma is the most common extracranial solid childhood tumor. Despite the availability of advanced multimodal therapy, high-risk patients still have low survival rates. p21-activated kinase 4 (PAK4) has been shown to regulate many cellular processes in cancer cells, including migration, polar...

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Detalles Bibliográficos
Autores principales: Li, Zhiheng, Li, Xiaolu, Xu, Lixiao, Tao, Yanfang, Yang, Chun, Chen, Xiaolan, Fang, Fang, Wu, Yi, Ding, Xin, Zhao, He, Li, Mei, Qian, Guanghui, Xu, Yunyun, Ren, Junli, Du, Weiwei, Wang, Jian, Lu, Jun, Hu, Shaoyan, Pan, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780023/
https://www.ncbi.nlm.nih.gov/pubmed/29048629
http://dx.doi.org/10.3892/or.2017.5989