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TGX-221 inhibits proliferation and induces apoptosis in human glioblastoma cells

Glioblastoma is the most common type of primary brain tumor in adults, with high mortality and morbidity rates. More effective therapeutic strategies are imperative. Previous studies have shown that the known p110-β-selective inhibitor TGX-221 blocks the activation of PKB/Akt in PTEN-deficient cells...

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Detalles Bibliográficos
Autores principales:	Yang, Xue, Yang, Ji-An, Liu, Bao-Hui, Liao, Jian-Ming, Yuan, Fan-En, Tan, Yin-Qiu, Chen, Qian-Xue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780035/ https://www.ncbi.nlm.nih.gov/pubmed/29048665 http://dx.doi.org/10.3892/or.2017.5991

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