Cargando…

Comparison of β-Cell Function Between Overweight/Obese Adults and Adolescents Across the Spectrum of Glycemia

OBJECTIVE: Type 2 diabetes is a growing health problem among both adults and adolescents. To better understand the differences in the pathogenesis of diabetes between these groups, we examined differences in β-cell function along the spectrum of glucose tolerance. RESEARCH DESIGN AND METHODS: We eva...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Melinda E., Chandramouli, Aaditya G., Considine, Robert V., Hannon, Tamara S., Mather, Kieren J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2018
Materias:	Pathophysiology/Complications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780051/ https://www.ncbi.nlm.nih.gov/pubmed/29183909 http://dx.doi.org/10.2337/dc17-1373

Ejemplares similares

Natural History of Insulin Sensitivity and Insulin Secretion in the Progression From Normal Glucose Tolerance to Impaired Fasting Glycemia and Impaired Glucose Tolerance: The Inter99 Study
por: Færch, Kristine, et al.
Publicado: (2009)

Primary Defects in β-Cell Function Further Exacerbated by Worsening of Insulin Resistance Mark the Development of Impaired Glucose Tolerance in Obese Adolescents
por: Cali, Anna M.G., et al.
Publicado: (2009)

The rs7903146 Variant in the TCF7L2 Gene Increases the Risk of Prediabetes/Type 2 Diabetes in Obese Adolescents by Impairing β-Cell Function and Hepatic Insulin Sensitivity
por: Cropano, Catrina, et al.
Publicado: (2017)

Leptin Is Associated With Exaggerated Brain Reward and Emotion Responses to Food Images in Adolescent Obesity
por: Jastreboff, Ania M., et al.
Publicado: (2014)

Glucose Effectiveness in Obese Children: Relation to Degree of Obesity and Dysglycemia
por: Weiss, Ram, et al.
Publicado: (2015)

Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 Individuals Across 13 Cohorts
por: DiCorpo, Daniel, et al.
Publicado: (2022)

Association of HLA-DQ Heterodimer Residues −18β and β57 With Progression From Islet Autoimmunity to Diabetes in the Diabetes Prevention Trial–Type 1
por: Zhao, Lue Ping, et al.
Publicado: (2022)

Retinal Arteriolar Dilation Predicts Retinopathy in Adolescents With Type 1 Diabetes
por: Cheung, Ning, et al.
Publicado: (2008)

Adipose Tissue Lipolysis Is Upregulated in Lean and Obese Men During Acute Resistance Exercise
por: Chatzinikolaou, Athanasios, et al.
Publicado: (2008)

Effects of Leptin Replacement Therapy on Pancreatic β-Cell Function in Patients With Lipodystrophy
por: Muniyappa, Ranganath, et al.
Publicado: (2014)

Co-occurrence of Risk Alleles in or Near Genes Modulating Insulin Secretion Predisposes Obese Youth to Prediabetes
por: Giannini, Cosimo, et al.
Publicado: (2014)

Spatial variations in gut permeability are linked to type 1 diabetes development in non-obese diabetic mice
por: Joesten, William C, et al.
Publicado: (2019)

Mechanistic Insights Into the Heterogeneity of Glucose Response Classes in Youths With Obesity: A Latent Class Trajectory Approach
por: Tricò, Domenico, et al.
Publicado: (2022)

Impact of Islet Autoimmunity on the Progressive β-Cell Functional Decline in Type 2 Diabetes
por: Brooks-Worrell, Barbara M., et al.
Publicado: (2014)

Type 1 Diabetes Is Associated With an Increased Risk of Fracture Across the Life Span: A Population-Based Cohort Study Using The Health Improvement Network (THIN)
por: Weber, David R., et al.
Publicado: (2015)

Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes
por: Sims, Emily K., et al.
Publicado: (2019)

Decreased miR-150 in obesity-associated type 2 diabetic mice increases intraocular inflammation and exacerbates retinal dysfunction
por: Yu, Fei, et al.
Publicado: (2020)

In Vivo Insulin Sensitivity and Secretion in Obese Youth: What are the differences between normal glucose tolerance, impaired glucose tolerance, and type 2 diabetes?
por: Bacha, Fida, et al.
Publicado: (2009)

Adipose and Muscle Tissue Profile of CD36 Transcripts in Obese Subjects Highlights the Role of CD36 in Fatty Acid Homeostasis and Insulin Resistance
por: Pietka, Terri A., et al.
Publicado: (2014)

Parity and type 2 diabetes mellitus: a study of insulin resistance and β-cell function in women with multiple pregnancies
por: Iversen, Ditte Smed, et al.
Publicado: (2016)

High Calorie Intake Is Associated With Worsening Insulin Resistance and β-Cell Function in Hispanic Women After Gestational Diabetes Mellitus
por: Chen, Zhanghua, et al.
Publicado: (2014)

High circulating plasma dipeptidyl peptidase- 4 levels in non-obese Asian Indians with type 2 diabetes correlate with fasting insulin and LDL-C levels, triceps skinfolds, total intra-abdominal adipose tissue volume and presence of diabetes: a case–control study
por: Anoop, Shajith, et al.
Publicado: (2017)

Impact of Early Diabetic Ketoacidosis on the Developing Brain
por: Aye, Tandy, et al.
Publicado: (2019)

Newly diagnosed type 2 diabetes in an ethnic minority population: clinical presentation and comparison to other populations
por: Morkos, Michael, et al.
Publicado: (2018)

Painful diabetic peripheral neuropathy: real-world comparison between topical treatment with lidocaine 700 mg medicated plaster and oral treatments
por: Überall, Michael, et al.
Publicado: (2022)

Prospective Associations of Vitamin D With β-Cell Function and Glycemia: The PROspective Metabolism and ISlet cell Evaluation (PROMISE) Cohort Study
por: Kayaniyil, Sheena, et al.
Publicado: (2011)

Risk Factors Related to Inflammation and Endothelial Dysfunction in the DCCT/EDIC Cohort and Their Relationship With Nephropathy and Macrovascular Complications
por: Lopes-Virella, Maria F., et al.
Publicado: (2008)

Testosterone Concentration in Young Patients With Diabetes
por: Chandel, Anil, et al.
Publicado: (2008)

Serum Xylosyltransferase Activity in Diabetic Patients as a Possible Marker of Reduced Proteoglycan Biosynthesis
por: Götting, Christian, et al.
Publicado: (2008)

Glucose and C-Peptide Changes in the Perionset Period of Type 1 Diabetes in the Diabetes Prevention Trial–Type 1
por: Sosenko, Jay M., et al.
Publicado: (2008)

Pregnancy Insulin, Glucose, and BMI Contribute to Birth Outcomes in Nondiabetic Mothers
por: Ong, Ken K., et al.
Publicado: (2008)

A1C Variability and the Risk of Microvascular Complications in Type 1 Diabetes: Data from the Diabetes Control and Complications Trial
por: Kilpatrick, Eric S., et al.
Publicado: (2008)

Euglycemic Hyperinsulinemia Alters the Response to Orthostatic Stress in Older Adults With Type 2 Diabetes
por: Madden, Kenneth M., et al.
Publicado: (2008)

Insulin Administration and Rate of Glucose Appearance in People With Type 1 Diabetes
por: Pennant, Mary E., et al.
Publicado: (2008)

Trends in High-Risk HLA Susceptibility Genes Among Colorado Youth With Type 1 Diabetes
por: Vehik, Kendra, et al.
Publicado: (2008)

Too Much Glucagon, Too Little Insulin: Time course of pancreatic islet dysfunction in new-onset type 1 diabetes
por: Brown, Rebecca J., et al.
Publicado: (2008)

Increased Shear Rate Resistance and Fastest Kinetics of Erythrocyte Aggregation in Diabetes Measured With Ultrasound
por: Cloutier, Guy, et al.
Publicado: (2008)

Acute Modulation of Toll-Like Receptors by Insulin
por: Ghanim, Husam, et al.
Publicado: (2008)

Progression of Cardiovascular Autonomic Dysfunction in Patients With Type 2 Diabetes: A 7-year follow-up study
por: Ko, Seung-Hyun, et al.
Publicado: (2008)

Prevalence and Risk Factors for Neuropathy in a Canadian First Nation Community
por: Bruce, Sharon G., et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_citqj9s3ohmndq7n9a0d84unku