Cargando…

Alanine scanning mutagenesis of SP70 epitope in characterizing species-specific antibodies induced by enterovirus 71-based antigens

The enterovirus 71 (EV71) SP70 epitope, derived from amino acids 208–222 of VP1, is a neutralizing epitope. The present study aimed to assess the inter-species differences of the antibodies induced by EV71-based antigens in responses to SP70 mutant peptides. BALB/c mice and Lou/C rats were immunized...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Meng, Zhang, Feng, Zhu, Yun, Gao, Limei, Jiang, Yunshui, Luo, Yongneng, Zhuang, Fangchang, Mao, Zian, Mao, Jiangsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780067/
https://www.ncbi.nlm.nih.gov/pubmed/29115505
http://dx.doi.org/10.3892/mmr.2017.7992