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DNA methyltransferase 3a modulates chemosensitivity to gemcitabine and oxaliplatin via CHK1 and AKT in p53-deficient pancreatic cancer cells

The aberrant expression of DNA methyltransferases (DNMTs) has been considered to be associated with pancreatic carcinogenesis and progression. DNMT3a is widely involved in cell proliferation and cell cycle progression in pancreatic ductal adenocarcinoma (PDAC) cells. However, its regulation of chemo...

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Detalles Bibliográficos
Autores principales:	Jing, Wei, Song, Na, Liu, Yunpeng, Qu, Xiujuan, Hou, Kezuo, Yang, Xianghong, Che, Xiaofang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780073/ https://www.ncbi.nlm.nih.gov/pubmed/29115606 http://dx.doi.org/10.3892/mmr.2017.7923

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