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Overexpression of miR-185 inhibits autophagy and apoptosis of dopaminergic neurons by regulating the AMPK/mTOR signaling pathway in Parkinson's disease

Parkinson's disease (PD) is an age-associated neurodegenerative disorder characterized by the death of dopaminergic neurons in the substantia nigra pars compacta. Activation of 5′-adenosine monophosphate-activated protein kinase (AMPK) has been suggested to be associated with PD pathogenesis. T...

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Detalles Bibliográficos
Autores principales: Wen, Zhi, Zhang, Jie, Tang, Peng, Tu, Ning, Wang, Ke, Wu, Guangyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780076/
https://www.ncbi.nlm.nih.gov/pubmed/29115479
http://dx.doi.org/10.3892/mmr.2017.7897