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Vitamin E (α-tocopherol) ameliorates aristolochic acid-induced renal tubular epithelial cell death by attenuating oxidative stress and caspase-3 activation

Aristolochic acid (AA) is a component identified in traditional Chinese remedies for the treatment of arthritic pain, coughs and gastrointestinal symptoms. However, previous studies have indicated that AA can induce oxidative stress in renal cells leading to nephropathy. α-tocopherol exists in numer...

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Detalles Bibliográficos
Autores principales: Wu, Tsai-Kun, Pan, Ying-Ru, Wang, Hsueh-Fang, Wei, Chyou-Wei, Yu, Yung-Luen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780138/
https://www.ncbi.nlm.nih.gov/pubmed/29115579
http://dx.doi.org/10.3892/mmr.2017.7921