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Human umbilical cord mesenchymal stem cells alleviate interstitial fibrosis and cardiac dysfunction in a dilated cardiomyopathy rat model by inhibiting TNF-α and TGF-β1/ERK1/2 signaling pathways

Dilated cardiomyopathy (DCM) is a disease of the heart characterized by pathological remodeling, including patchy interstitial fibrosis and degeneration of cardiomyocytes. In the present study, the beneficial role of human umbilical cord-derived mesenchymal stem cells (HuMSCs) derived from Wharton&#...

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Detalles Bibliográficos
Autores principales: Zhang, Changyi, Zhou, Guichi, Chen, Yezeng, Liu, Sizheng, Chen, Fen, Xie, Lichun, Wang, Wei, Zhang, Yonggang, Wang, Tianyou, Lai, Xiulan, Ma, Lian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780147/
https://www.ncbi.nlm.nih.gov/pubmed/29115435
http://dx.doi.org/10.3892/mmr.2017.7882