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Cytochrome P450 1A1 and 1B1 promoter CpG island methylation regulates rat liver injury induced by isoniazid

DNA methylation is an important component of epigenetics that is involved in the occurrence and development of a variety of diseases. The present study aimed to clarify the relationship between cytochrome P450 (CYP)1A1 and CYP1B1 promoter CpG island methylation and isoniazid-induced liver injury in...

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Detalles Bibliográficos
Autores principales: Li, Yanhui, Li, Yuhong, Zheng, Guoying, Zhu, Lingyan, Wang, Jishun, Mu, Shasha, Ren, Qi, Feng, Fumin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780152/
https://www.ncbi.nlm.nih.gov/pubmed/29115507
http://dx.doi.org/10.3892/mmr.2017.7929