Allopregnanolone suppresses mechanical allodynia and internalization of neurokinin-1 receptors at the spinal dorsal horn in a rat postoperative pain model

BACKGROUND: To identify a new strategy for postoperative pain management, we investigated the analgesic effects of allopregnanolone (Allo) in an incisional pain model, and also assessed its effects on the activities of the primary afferent fibers at the dorsal horn. METHODS: In experiment 1, 45 rats...

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Detalles Bibliográficos
Autores principales: Fujita, Masahide, Fukuda, Taeko, Sato, Yasuhiro, Takasusuki, Toshifumi, Tanaka, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Pain Society 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780210/
https://www.ncbi.nlm.nih.gov/pubmed/29372021
http://dx.doi.org/10.3344/kjp.2018.31.1.10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780210/
https://www.ncbi.nlm.nih.gov/pubmed/29372021
http://dx.doi.org/10.3344/kjp.2018.31.1.10

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