Cargando…

Characterization of the multimeric structure of poly(A)-binding protein on a poly(A) tail

Eukaryotic mature mRNAs possess a poly adenylate tail (poly(A)), to which multiple molecules of poly(A)-binding protein C1 (PABPC1) bind. PABPC1 regulates translation and mRNA metabolism by binding to regulatory proteins. To understand functional mechanism of the regulatory proteins, it is necessary...

Descripción completa

Detalles Bibliográficos
Autores principales: Sawazaki, Ryoichi, Imai, Shunsuke, Yokogawa, Mariko, Hosoda, Nao, Hoshino, Shin-ichi, Mio, Muneyo, Mio, Kazuhiro, Shimada, Ichio, Osawa, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780489/
https://www.ncbi.nlm.nih.gov/pubmed/29362417
http://dx.doi.org/10.1038/s41598-018-19659-6