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Dynamic recruitment of ubiquitin to mutant huntingtin inclusion bodies

Many neurodegenerative diseases, such as Huntington’s disease, are hallmarked by the formation of intracellular inclusion bodies (IBs) that are decorated with ubiquitin, proteasomes and chaperones. The apparent enrichment of ubiquitin and components involved in protein quality control at IBs suggest...

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Detalles Bibliográficos
Autores principales:	Juenemann, Katrin, Jansen, Anne H. P., van Riel, Luigi, Merkx, Remco, Mulder, Monique P. C., An, Heeseon, Statsyuk, Alexander, Kirstein, Janine, Ovaa, Huib, Reits, Eric A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780509/ https://www.ncbi.nlm.nih.gov/pubmed/29362455 http://dx.doi.org/10.1038/s41598-018-19538-0

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