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A Proteomic-Based Approach to Study the Mechanism of Cytotoxicity Induced by Interleukin-1α and Cycloheximide

ABSTRACT: The exposure of HeLa cells to interleukin-1 alpha (IL-1α) in the presence of cycloheximide (CHX) leads to the release of active tumor necrosis factor alpha (TNF-α), eliciting cytocidal effect on these cells. A mass spectrometry (MS)-based analysis of the qualitative proteomic profiles of t...

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Detalles Bibliográficos
Autores principales:	Macur, Katarzyna, Grzenkowicz-Wydra, Jolanta, Konieczna, Lucyna, Bigda, Jacek, Temporini, Caterina, Tengattini, Sara, Bączek, Tomasz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2017
Materias:	Original
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780535/ https://www.ncbi.nlm.nih.gov/pubmed/29398714 http://dx.doi.org/10.1007/s10337-017-3382-3

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