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Liver Disease in Alpha-1 Antitrypsin Deficiency: Current Approaches and Future Directions

PURPOSE OF REVIEW: The aim of the study is to review the liver disease caused by alpha-1 antitrypsin deficiency (A1ATD), including pathogenesis, epidemiology, diagnostic testing, and recent therapeutic developments. RECENT FINDINGS: Therapeutic approaches target several intracellular pathways to red...

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Detalles Bibliográficos
Autores principales: Mitchell, Ellen L., Khan, Zahida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780543/
https://www.ncbi.nlm.nih.gov/pubmed/29399420
http://dx.doi.org/10.1007/s40139-017-0147-5