Alteration of hepatocellular antioxidant gene expression pattern and biomarkers of oxidative damage in diazinon-induced acute toxicity in Wistar rat: A time-course mechanistic study

In the present survey, the plasma level of diazinon after acute exposure was measured by HPLC method at a time-course manner. In addition, the impact of diazinon on the expression of the key genes responsible for hepatocellular antioxidative defense, including PON1, GPx and CAT were investigated. Th...

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Detalles Bibliográficos
Autores principales: Hassani, Shokoufeh, Maqbool, Faheem, Salek-Maghsoudi, Armin, Rahmani, Soheila, Shadboorestan, Amir, Nili-Ahmadabadi, Amir, Amini, Mohsen, Norouzi, Parviz, Abdollahi, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780620/
https://www.ncbi.nlm.nih.gov/pubmed/29383019
http://dx.doi.org/10.17179/excli2017-760

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