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Pyrroline-5-carboxylate reductase 1 promotes proliferation and inhibits apoptosis in non-small cell lung cancer

Disordered tumor cell metabolism is involved in the process of tumorigenesis. Proline metabolism is of critical importance for tumor cells, and pyrroline-5-carboxylate reductase 1 (PYCR1), a key proline biosynthesis enzyme, has been reported to be overexpressed in prostate cancer and to promote tumo...

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Detalles Bibliográficos
Autores principales: Cai, Feng, Miao, Yingying, Liu, Chenyang, Wu, Ting, Shen, Simei, Su, Xin, Shi, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780737/
https://www.ncbi.nlm.nih.gov/pubmed/29403556
http://dx.doi.org/10.3892/ol.2017.7400