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Cellulose acetate phthalate, a common pharmaceutical excipient, inactivates HIV-1 and blocks the coreceptor binding site on the virus envelope glycoprotein gp120

BACKGROUND: Cellulose acetate phthalate (CAP), a pharmaceutical excipient used for enteric film coating of capsules and tablets, was shown to inhibit infection by the human immunodeficiency virus type 1 (HIV-1) and several herpesviruses. CAP formulations inactivated HIV-1, herpesvirus types 1 (HSV-1...

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Detalles Bibliográficos
Autores principales: Neurath, A Robert, Strick, Nathan, Li, Yun-Yao, Debnath, Asim K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC57811/
https://www.ncbi.nlm.nih.gov/pubmed/11602021
http://dx.doi.org/10.1186/1471-2334-1-17

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