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Choroidal Thickness in Healthy Subjects

PURPOSE: To measure the choroidal thickness by enhanced depth imaging optical coherence tomography (EDI-OCT) in normal eyes. METHODS: In a prospective case series, 208 eyes of 104 normal Iranian subjects were enrolled. Complete ophthalmic examination was performed. Inclusion criteria were best corre...

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Autores principales: Entezari, Morteza, Karimi, Saeed, Ramezani, Alireza, Nikkhah, Homayoun, Fekri, Yousef, Kheiri, Bahareh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5782455/
https://www.ncbi.nlm.nih.gov/pubmed/29403588
http://dx.doi.org/10.4103/jovr.jovr_148_16
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author Entezari, Morteza
Karimi, Saeed
Ramezani, Alireza
Nikkhah, Homayoun
Fekri, Yousef
Kheiri, Bahareh
author_facet Entezari, Morteza
Karimi, Saeed
Ramezani, Alireza
Nikkhah, Homayoun
Fekri, Yousef
Kheiri, Bahareh
author_sort Entezari, Morteza
collection PubMed
description PURPOSE: To measure the choroidal thickness by enhanced depth imaging optical coherence tomography (EDI-OCT) in normal eyes. METHODS: In a prospective case series, 208 eyes of 104 normal Iranian subjects were enrolled. Complete ophthalmic examination was performed. Inclusion criteria were best corrected visual acuity (BCVA) ≥20/20, ≤ ±1 diopter of refractive error in either spherical or cylindrical components, normal intraocular pressure (IOP) and no systemic or ocular diseases. The choroidal thickness was measured by EDI-OCT subfoveally, and 1500 μm and 3000 μm nasal and temporal to the fovea. RESULTS: Mean age was 34.6 ± 9.8 years (range, 18–57 years). Mean subfoveal choroidal thickness was 363 ± 84 μm. Choroidal thickness was 292 ± 76 and 194 ± 58 μm at 1500 and 3000 μm nasal to the fovea, respectively, and 314 ± 77 and 268 ± 66 μm at 1500 and 3000 μm temporal to the fovea, respectively. There was no statistically significant difference in the choroidal thickness between sexes and laterality of the eyes. Choroidal thickness at fovea (P < 0.001) and at all extrafoveal locations decreased significantly for every 10 years increase in age. CONCLUSION: In normal Iranian subjects participating in this study, mean choroidal thickness was comparable with other reports.
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spelling pubmed-57824552018-02-05 Choroidal Thickness in Healthy Subjects Entezari, Morteza Karimi, Saeed Ramezani, Alireza Nikkhah, Homayoun Fekri, Yousef Kheiri, Bahareh J Ophthalmic Vis Res Original Article PURPOSE: To measure the choroidal thickness by enhanced depth imaging optical coherence tomography (EDI-OCT) in normal eyes. METHODS: In a prospective case series, 208 eyes of 104 normal Iranian subjects were enrolled. Complete ophthalmic examination was performed. Inclusion criteria were best corrected visual acuity (BCVA) ≥20/20, ≤ ±1 diopter of refractive error in either spherical or cylindrical components, normal intraocular pressure (IOP) and no systemic or ocular diseases. The choroidal thickness was measured by EDI-OCT subfoveally, and 1500 μm and 3000 μm nasal and temporal to the fovea. RESULTS: Mean age was 34.6 ± 9.8 years (range, 18–57 years). Mean subfoveal choroidal thickness was 363 ± 84 μm. Choroidal thickness was 292 ± 76 and 194 ± 58 μm at 1500 and 3000 μm nasal to the fovea, respectively, and 314 ± 77 and 268 ± 66 μm at 1500 and 3000 μm temporal to the fovea, respectively. There was no statistically significant difference in the choroidal thickness between sexes and laterality of the eyes. Choroidal thickness at fovea (P < 0.001) and at all extrafoveal locations decreased significantly for every 10 years increase in age. CONCLUSION: In normal Iranian subjects participating in this study, mean choroidal thickness was comparable with other reports. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC5782455/ /pubmed/29403588 http://dx.doi.org/10.4103/jovr.jovr_148_16 Text en Copyright: © 2018 Journal of Ophthalmic and Vision Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Entezari, Morteza
Karimi, Saeed
Ramezani, Alireza
Nikkhah, Homayoun
Fekri, Yousef
Kheiri, Bahareh
Choroidal Thickness in Healthy Subjects
title Choroidal Thickness in Healthy Subjects
title_full Choroidal Thickness in Healthy Subjects
title_fullStr Choroidal Thickness in Healthy Subjects
title_full_unstemmed Choroidal Thickness in Healthy Subjects
title_short Choroidal Thickness in Healthy Subjects
title_sort choroidal thickness in healthy subjects
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5782455/
https://www.ncbi.nlm.nih.gov/pubmed/29403588
http://dx.doi.org/10.4103/jovr.jovr_148_16
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