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ADAMTS13 Deficiency Worsens Colitis and Exogenous ADAMTS13 Administration Decreases Colitis Severity in Mice
Background Inflammatory bowel disease (IBD) affects 1.6 million people in the United States. IBD is associated with an increased risk of thrombosis, which rises with disease activity. The pathogenesis of IBD and its increased thrombotic risk is not completely understood. Ultra large von Willebrand...
Autores principales: | Zitomersky, Naamah L., Demers, Melanie, Martinod, Kimberly, Gallant, Maureen, Cifuni, Stephen M., Biswas, Amlan, Snapper, Scott, Wagner, Denisa D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Georg Thieme Verlag KG
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5782810/ https://www.ncbi.nlm.nih.gov/pubmed/29376146 http://dx.doi.org/10.1055/s-0037-1603927 |
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